The good industrial hygiene performance of pharmaceutical equipment is not only related to pharmaceutical production safety and occupational health risks, but also to production quality control and equipment operation and maintenance costs.

Different from the occupational exposure assessment that evaluates the exposure level of occupational hazards of employees, the containment effect assessment is based on the equipment, and the containment effect of the equipment when dealing with hazardous materials is evaluated. The substitution test is to use substitutes or substitute compounds to simulate the activity. Pharmaceutical ingredients (API, active Pharmaceutical ingredident) and/or excipients (inactive ingredients), an effective tool for verifying device containment levels.

How is the assessment process implemented for industrial hygiene technicians in pharmaceutical companies? What surrogates and sampling methods and equipment to use? How to analyze the sampling results in order to get the correct evaluation results, so as to pass the acceptance, and then reduce the cost and risk of the enterprise?

This SafeBridge free sharing class will be answered through the following explanations:

1. Introduction to alternative testing and selection of alternatives

2. Implement containment effectiveness assessment procedures

3. Sampling method and key points

4. Sampling data processing and analysis

Founded in 1997, SafeBridge has been providing EHS consulting and laboratory analysis services to the North American and European pharmaceutical industries for over 20 years. Its consulting team consists of toxicologists, industrial hygienists, chemists, and experienced pharmaceutical industry safety and environmental professionals. The well-known Control Banding tool is their first.

Safebridge's star course Potent Compound Safety Boot Camps (highly active compound safety training) have been successfully held in India, San Diego, Boston, Chicago, Liverpool and other countries and cities.

In 2019, after being strongly invited by Beeree and repeatedly communicating with Beeree, in order to solve the health and safety risks of APIs and provide solutions for the vast number of pharmaceutical and API manufacturers in China, SafeBridge came to China for the first time with the safety training of highly active compounds. The two-day training in Shanghai attracted technicians and executives from well-known pharmaceutical companies from Singapore, Taiwan and the mainland to attend the conference. After that, SafeBridge maintained friendly relations with Beeree.